Studies indicate that people who take proton pump inhibitor medications (such as Nexium) may be at an increased risk for broken bones. The risk appears to be highest for people who take such medications at high doses or for long periods (over a year). You and your healthcare provider should take this into account when deciding if the benefits of this medication outweigh the risks for your particular situation.

The use of proton pump inhibitors (including this medication) may increase the risk of a potentially serious condition known as Clostridium difficile-associated diarrhea (CDAD). If you develop diarrhea that does not seem to improve (especially if it is watery and accompanied by a fever and abdominal pain), seek immediate medical attention.

The prominent consumer watchdog group Public Citizen has filed a petition with the FDA, indicating that a new black box warning for Nexium, Prilosec and other proton pWe bring forth an array of Antacid Medicines that are formulated by dexterous professionals who are guided by medical experts. Available in syrup form, these antacids are consumed for counteracting stomach acidity. Moreover, these act as stomach acid neutralizers, which reduces or blocks the secretion of acid driven by gastric cells. In order to meet urgent demands of the clients, we have these antacids available in bulk quantity with us. Free from any kind of side-effect, these products are ensured for their longer shelf life and ability to improve consumers' health.

The Magaldrate and Simethicone Oral Suspension (Antacid Drugs) that we manufacture and supply are used to relieve several stomach problems. Their main purpose is to neutralize excess stomach acid. They are highly effective in providing quick relief and for a longer period of time.

Treating acid indigestion, heartburn, gas, and sour stomach. It may also be used for other conditions as determined by your doctor.

Magaldrate/simethicone suspension is an antacid and antiflatulent combination. The antacid works by neutralizing stomach acid and increasing the pH of the stomach. The antiflatulent works by breaking up gas bubbles, which makes gas easier to eliminate.

This may not be a complete list of all interactions that may occur. Ask your health care provider if magaldrate/simethicone suspension may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.ump inhibitor drugs is necessary to warn consumers and the medical community about the risk of long-term dependence and other dangerous side effects.

According to the petition (PDF) filed with the FDA on Tuesday, Public Citizen indicates that the strongest possible warning label is necessary for the widely used acid reflux drugs, which were prescribed more than 119 million times in 2009 and generated sales in the United States of $13.6 billion.

An estimated one out of every 20 people in the developed world are currently taking a proton pump inhibitor (PPI) to reduce the production of stomach acid in an attempt to alleviate symptoms of gastroesophageal reflux disease (GERD), ulcers and other stomach ailments. In addition to Nexium and Prilosec, other drugs in the same class included Prevacid, Zegerid, Protonix, Dexilant, Aciphex, Vimovo and a number of generic equivalents.

Riginic is a brand name medication included in a group of medications called Magnesium compounds. For more information about Magnesium Carbonate see its generics: Aluminium Hydroxide, Magnesium Carbonate.

This medication is used to treat the symptoms of too much stomach acid such as stomach upset, heartburn, and acid indigestion. It is also used to relieve symptoms of extra gas such as belching, bloating, and feelings of pressure/discomfort in the stomach/gut. Simethicone helps break up gas bubbles in the gut. Aluminum and magnesium antacids work quickly to lower the acid in the stomach. Liquid antacids usually work faster/better than tablets or capsules.

This medication works only on existing acid in the stomach. It does not prevent acid production. It may be used alone or with other medications that lower acid production (e.g., H2 blockers such as cimetidine/ranitidine and proton pump inhibitors such as omeprazole).

If you are self-treating with this medication, carefully read the package instructions before you start using this product to be sure it is right for you. Some products have similar brand names but different active ingredients with different uses. Taking the wrong product could harm you. Ask your pharmacist if you have any questions about your product or its use.

How to use Riginic

Take this medication by mouth, usually after meals and at bedtime as needed. Follow all the directions on the product package or use as directed by your doctor. If you are uncertain about any of this information, consult your doctor or pharmacist.

If you are taking the chewable tablets, chew thoroughly before swallowing, then drink a full glass of water (8 ounces or 240 milliliters).

If you are using the liquid form of this medication, shake the bottle well before pouring each dose. Refrigerating the suspension may improve the flavor. Do not freeze. The liquid form works best if taken without other fluids. You can mix your dose with a little water if needed.

This product may react with other medications (including digoxin, iron, pazopanib, tetracycline antibiotics, quinolone antibiotics such as ciprofloxacin), preventing them from being fully absorbed by your body. Talk with your doctor or pharmacist about how to schedule your medications to prevent this problem.

If your acid problems persist or worsen after you have used this product for 1 week, or if you think you have a serious medical problem, seek immediate medical attention. If you are using this medication regularly on a daily basis for more than 2 weeks, you may have a medical problem that needs different treatment. Ask your doctor whether this is the right medication for you.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA

Consult your pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada.

What should I know regarding pregnancy, nursing and administering Riginic to children or the elderly?
If you are:
Pregnant:

FDB Only When Necessary: INSUFFICIENT DATA AVAILABLE

FDB Only When Necessary: AVOID CHRONIC HIGH DOSE
Nursing:

No Known Risk: POOR GI ABSORPTION

No Known Risk: EXCRETED IN ANIMAL STUDIES;POOR GI ABSORPTION
An adult over 60:

Precaution: MAY CAUSE DIARRHEA. CAUTION IN RENAL IMPAIRMENT.

Precaution: MAY CAUSE CONSTIPATION. OVER USE MAY AFFECT BONE MINERALIZATION.
Giving Riginic to a child under 12:

Warning: RARE RISK OF OSTEOMALACIA WITH HIGH DOSE THERAPY.

Relative Contraindication: NOT RECOMMENDED UNDER 6YRS OF AGE UNLESS PROPERLY DIAGNOSED.

Does Riginic interact with other medications?
Riginic may interact with the following medications:
Serious Interactions of Riginic:

These medications may interact and cause very harmful effects. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

ALUMINUM & MAGNESIUM CONTAINING ANTACIDS/RALTEGRAVIR
ANTACIDS; H2 ANTAGONISTS; PROTON PUMP INHIBITORS/ULIPRISTAL
ALUMINUM; CALCIUM; MAGNESIUM/PHOSPHATE SUPPLEMENTS
ALUMINUM SALTS/SELECTED CHELATION AGENTS
ANTACIDS; LANTHANUM/SELECTED AZOLE ANTIFUNGALS
DIVALENT & TRIVALENT CATIONS/TETRACYCLINES

If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Notes

No monograph available at this time.

Missed Dose

Consult your pharmacist.

Storage

Consult your pharmacist.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

Information last revised March 2013. Copyright(c) 2013 First Databank, Inc.