AMPHETAMINES HAVE A HIGH POTENTIAL FOR ABUSE. ADMINISTRATION OF AMPHETAMINES FOR PROLONGED PERIODS OF TIME MAY LEAD TO DRUG DEPENDENCE AND MUST BE AVOIDED. PARTICULAR ATTENTION SHOULD BE PAID TO THE POSSIBILITY OF SUBJECTS OBTAINING AMPHETAMINES FOR NON-THERAPEUTIC USE OR DISTRIBUTION TO OTHERS, AND THE DRUGS SHOULD BE PRESCRIBED OR DISPENSED SPARINGLY. MISUSE OF AMPHETAMINES MAY CAUSE SUDDEN DEATH AND SERIOUS CARDIOVASCULAR ADVERSE EVENTS.

Treating attention deficit hyperactivity disorder (ADHD) in children. It is also used to treat a type of sleep disorder (narcolepsy). It may also be used for other conditions as determined by your doctor.

Dextroamphetamine is a central nervous system stimulant. Exactly how it works is not known. It affects certain chemicals in the brain, which may help to improve attention span and behavior.

Side effects

The Cochrane Collaboration review on amphetamines for ADHD suggests that dextroamphetamine and other amphetamine mixtures have the same incidence of adverse events.

Physical

At normal therapeutic doses, the physical side effects of amphetamine vary widely by age and among individual people. Cardiovascular side effects can include irregular heartbeat (usually increased heart rate), hypertension (high blood pressure) or hypotension (low blood pressure) from a vasovagal response, and Raynaud's phenomenon.Sexual side effects in males may include erectile dysfunction, frequent erections, or prolonged erections. Other potential side effects include abdominal pain, acne, blurred vision, excessive grinding of the teeth, profuse sweating, dry mouth, loss of appetite, nausea, reduced seizure threshold, tics, and weight loss.Dangerous physical side effects are rare in typical pharmaceutical doses

Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to other sympathomimetic amines (such as epinephrine, ephedrine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: blood circulation problems (such as Raynaud's disease), certain mental/mood conditions (such as severe agitation, psychosis), personal/family history of mental/mood disorders (such as bipolar disorder, depression, psychotic disorder, suicidal thoughts), heart problems (including irregular heartbeat/rhythm, coronary artery disease, heart failure

What other drugs could interact with Dexedrine?

There may be an interaction between dextroamphetamine and any of the following:

acetazolamide
antihistamines
barbiturates (e.g., phenobarbital)
beta-blockers (e.g., propranolol)
chlorpromazine
ethosuximide
guanethidine
haloperidol
hydrochlorothiazide
lithium
MAO inhibitors (e.g., phenelzine, tranylcypromine)

medications that treat high blood pressure
meperidine
methenamine
norepinephrine
other medications for ADHD
phenytoin
propoxyphene
sympathomimetic medications (e.g., epinephrine, pseudoephedrine)
tricyclic antidepressants (e.g., amitriptyline)
urinary tract acidifiers (e.g., ammonium chloride) and alkalinizers (e.g., potassium citrate)

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

stop taking one of the medications,
change one of the medications to another,
change how you are taking one or both of the medications, or
leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Overdose

An amphetamine overdose can lead to many different symptoms, but is rarely fatal with appropriate care.A moderate overdose may induce symptoms including brisk reflexes, confusion, high or low blood pressure, hyperthermia, inability to urinate, involuntary muscle twitching, irregular heartbeat, muscle pain, painful urination, rapid breathing, and severe agitation.An extremely large overdose may produce symptoms such as amphetamine psychosis, bleeding in the brain, cardiogenic shock, circulatory collapse, compulsive and repetitive behavior, elevated blood potassium or low blood potassium, extreme fever, fluid accumulation in the lungs, high lung arterial blood pressure, kidney failure, metabolic acidosis, no urine production, rapid muscle breakdown, respiratory alkalosis, serotonin toxidrome, and sympathomimetic toxidrome.[sources 3] Fatal amphetamine poisoning usually involves convulsions and coma