{"id":11742,"date":"2016-09-19T07:28:24","date_gmt":"2016-09-19T07:28:24","guid":{"rendered":"http:\/\/www.biphoo.com\/bipnews\/?p=11742"},"modified":"2016-09-19T12:32:59","modified_gmt":"2016-09-19T12:32:59","slug":"new-antibiotic-gel-may-cure-ear-infections-children","status":"publish","type":"post","link":"https:\/\/www.biphoo.com\/bipnews\/health\/new-antibiotic-gel-may-cure-ear-infections-children.html","title":{"rendered":"New antibiotic gel may cure ear infections in children"},"content":{"rendered":"

New antibiotic gel may cure ear infections in children | \u00a0Best doc tips for health\u00a0<\/strong><\/span><\/h2>\n

A new antibiotic gel may cure ear infections in children 2016<\/strong> :- A single dose of a bioengineered gel, developed by US researchers, could deliver a full course of antibiotic therapy for a common childhood ear infection, a preclinical study has found. Middle ear infection, or otitis media, is an ear infection that is usually caused by bacteria or viruses. Common symptoms include ear pain and fever and in some cases, it may also cause drainage of fluid from the ear or hearing loss. Although most ear infections go away on their own, some require antibiotics.<\/span><\/p>\n

As high doses of oral antibiotics are needed to get to the ear, side effects like diarrhea, rashes, and oral thrush are common. \u201cWith oral antibiotics, you have to treat the entire body repeatedly just to get to the middle ear,\u201d said Rong Yang, Ph.D., a chemical engineer at Boston Children\u2019s Hospital in Massachusetts, US. However, \u201cwith the gel, a pediatrician can administer the entire antibiotic course all at once, and only where it\u2019s needed,\u201d Yang said.<\/span>
\nSquirted into the ear canal, the gel quickly hardens and stays in place, gradually dispensing antibiotics across the eardrum into the middle ear. \u201cOur technology gets things across the eardrum that don\u2019t usually get across in sufficient quantity to be therapeutic,\u201d added Daniel Kohane from Boston Children\u2019s Hospital.<\/span><\/p>\n

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Previously, the eardrum (also called the tympanic membrane) was an impenetrable barrier, but the bioengineered gel gets drugs past it with the help of chemical permeation enhancers (CPEs). The CPEs insert themselves into the membrane, opening up molecular pores that allow the antibiotics to seep through to the eardrum\u2019s outermost layer.<\/span><\/p>\n

\u201cTranstympanic delivery of antibiotics to the middle ear has the potential to enable children to benefit from the rapid antibacterial activity of antimicrobial agents without systemic exposure and could reduce the emergence of resistant microbes,\u201d noted Stephen Pelton, the paediatrician at Boston Medical Center.<\/span><\/p>\n

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The findings, published in the journal Science Translational Medicine, have led to better, easier and potentially safer treatment for middle ear infections, the researchers concluded.<\/span><\/p>\n

Source<\/strong>:http:\/\/indianexpress.com\/article\/lifestyle\/health\/new-antibiotic-gel-may-cure-ear-infections-in-children-3037780\/<\/span><\/p>\n

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